女性心绞痛比男性更常见

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MedWire News: Women are more likely than men to suffer angina, a meta-analysis of data from various countries shows.
MedWire新闻：来自不同国家的所有分析数据表明,女人比男人更容易患上心绞痛.

\"Understanding the dichotomy of why men, who have a universal excess of fatal myocardial infarction (MI), do not have an excess of angina presents an important challenge for further research,\" the authors write in the journal Circulation.
\"解释为什么男人患上致命性心肌梗塞后普遍不易患上心绞痛这种现象,对它的进一步研究是一个很大的挑战\",Circulation杂志的作者按.

Harry Hemingway (University College London Medical School, UK) and colleagues carried out a meta-analysis of 74 population studies to examine the prevalence of angina in women and men across 31 countries and the rate of mortality due to MI.
Harry Hemingway（英国伦敦大学医学院）和他的同事研究了31个国家的妇女和男人心绞痛的流行程度和由于心肌梗塞而死的比率,通过研究74种人,完成了这项分析.

Only studies that reported the prevalence of angina using the Rose angina questionnaire were included, with a total of 74 reports of 13,331 angina cases in women and 11,511 cases in men.
心绞痛流行的研究报告使用Rose心绞痛调查问卷，总共74份报告,13331例关于妇女的心绞痛,11511例是男性的。

Angina prevalence varied widely across populations, from 0.73% to 14.4% in women and from 0.76% to 15.1% in men. The population weighted mean was 6.7% in women and 5.7% in men.
不通人种易患心绞痛相差很大,妇女从0.73 ％至14.4 ％, 男性从0.76 ％至15.1 ％.人口加权均值女性是6.7 ％,男性是5.7 ％.

Women were significantly more likely than men to have angina, with a pooled random-effects gender ratio of 1.20 (p<0.0001).
汇集的性别比例的随机影响为1.20（ P < 0.0001 ）,说明妇女比男人更容易有心绞痛.

This female excess was found across countries with widely differing rates of MI mortality in women (interquartile range 12.7 to 126.5 per 100 000). MI mortality in women was particularly high in American studies, and higher among non-White ethnic groups than in Whites.
在不同的国家之间,妇女普遍有着不同的心肌梗塞死亡率（ interquartile范围从十万分之12.7到十万分之126.5）.在美国的研究中, 妇女因心肌梗塞而死亡的比率普遍较高,其中非白种人高于白人.

This increased prevalence of angina in women did not differ significantly after adjusting for age, the year the survey began, or the gender ratio for mortality due to MI.
在调查开始时,将年龄调整后,心绞痛的流行程度的增加,在妇女身上并无明显差异,或者因心肌梗塞而死亡的男女比例并无差异.

Hemingway et al conclude: \"Over time and at different ages, independent of diagnostic and treatment practices, women have a similar or slightly higher prevalence of angina than men across countries with widely differing MI mortality rates.\"
Hemingway等人的结论是：\"随着时间的推移和处于不同的年龄，使用独立的诊断和治疗手法，各个国家有着不同的心肌梗塞死亡率的妇女,比男人有类似或略高一点的易患心绞痛\".

They add: \"Further research is required to establish whether risk factors that are unique to women, that are more common in women, or that have stronger effects in women, as well as their underlying genetic basis, predict angina compared with MI.\"
他们补充：\"需要进一步的研究,确定在妇女身上是否有独特的危险因素,这些因素在妇女当中更普遍存在,或对妇女有更强的影响,以及其潜在的遗传基础,去预测心绞痛.

Circulation 2008; 117: 1526-1536
Circulation 2008; 117卷 ： 1526页-1536页