Blood-Spinal Cord and Brain Barriers in Health and Disease

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Blood-Spinal Cord and Brain Barriers in Health and Disease
By Hari Shanker Sharma

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Publisher:  Academic Press
Number Of Pages:  608
Publication Date:  2003-09
ISBN-10 / ASIN:  0126390118
ISBN-13 / EAN:  9780126390117
Binding:  Hardcover


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Product Description:

Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma.

Key Features
* Presents the recent progress made in the research on the blood-brain and spinal cord barrier
* Contains numerous illustrations of light and electron micrographs
* Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro




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Summary: Probably the best single book to date on the subject
Rating: 4

FULL DISCLOSURE--I work closely with several of the contributing authors in this book.

This book has been an indispensible resource in the preparation of my doctoral dissertation, which is on the blood-brain barrier. I would heartily recommend it to anyone interested in the field at the graduate student level or higher. The treatment of some subjects is a little uneven, but that is to be expected in a book that covers so much ground--from molecular biology and biophysics of tight junction proteins to clinical aspects of the BBB--in a single volume. The illustrations are attractive and clear, and most of the chapters are very well-written.

Overall, an excellent reference for researchers in the BBB field, and a great introduction to many aspects of the field for scientists or clinicians wanting to know more about it.

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