糖尿病的新治疗希望； 青蛙皮肤

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Frog Skin Provides Hope For A New Diabetes Teatment
Date: Tuesday, March 11 @ 15:24:37 CST
Just as the spit from the Gila Monster has provided a treatment for diabetes, now skin secretions from a South American \"\"shrinking\"\" frog could be used to treat type 2 diabetes also.
正像毒蜥可以作为糖尿病的一种治疗一样，现在，南美“皱缩“的青蛙皮肤分泌物也能用来治疗2型糖尿病
A compound isolated from the frog, which grows to 27cm as a tadpole before shrinking to 4cm in adulthood, stimulates insulin release. A synthetic version of the compound - pseudin-2 - could be used to produce new drugs, delegates at the Diabetes UK annual conference heard.
英国糖尿病协会年会代表得知，一种混合的pseudin-2合成品，可以用来制造新药，从成年期皱缩为4公分，蝌蚪期为27公分的青蛙，分离出的混合物，可以刺激胰岛素释放。
Scientists from the University of Ulster and United Arab Emirates University have tested a synthetic version of pseudin-2, a compound which protects the paradoxical frog from infection.
Ulster and United Arab Emirates 大学的科学家们，试验了pseudin-2, 合成品 , 该合成品能防止荒谬的青蛙感染
More research is needed, but there is a growing body of work around natural anti-diabetic drug discovery that, as you can see, is already yielding fascinating results.
需要进一步研究，不过，一种天然的抗糖尿病的药物正在生成，已经产生了迷人的结果
They found it stimulated the secretion of insulin in pancreatic cells in the laboratory.
他们发现，在实验室这种天然物能刺激胰腺细胞分泌胰岛素。
And importantly, there were no toxic effects on the cells. The synthetic version was better at stimulating insulin than the natural compound, opening the way for it potential development as a drug for treating diabetes.
重要的是，对细胞没有毒性。合成品刺激胰岛素比天然混合物更好，为开发糖尿病治疗药物的可能性开创了新路
Study leader Dr. Yasser Abdel-Wahab, senior lecturer in biomedical sciences at the University of Ulster, said there had been a lot of research into bioactive molecules from amphibian skin secretions. One recently developed diabetes drug - exenatide - was developed from a hormone in the saliva of the Gila monster.
研究领导者，阿尔斯特大学高级讲师Dr. Yasser Abdel-Wahab, 说对来自两栖动物皮肤分泌物的活性分子已经作了很多研究，最近开发的一种糖尿病药exenatide ，就是从毒蜥的唾液激素开发出来的
\"\"We found that it stimulated the secretion of insulin and that the synthetic version is more potent that pseudin-2 itself.
我们发现，它刺激胰岛素分泌，合成品比pseudin-2 本身更有效



估计青蛙也具有种属特异性，应该某种特定类型吧。还记得当年有日本科学家研究发现某种南瓜（好像是产于北海道的）能有改善血糖作用，不知道引起了多少“吃南瓜能降血糖”的谬论，吃到酮症酸中毒了还不罢休，至今还有余毒在流传。所以真的希望这条新闻能够带来科学的治疗方法，而不要误导患者，更不要成为某些“能治愈糖尿病”的骗子的“理论基础”。