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[【学科前沿】] 锻炼促进胰岛制造细胞功能

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发表于 2008-4-9 06:17:20 | 显示全部楼层 |阅读模式
Workouts Boost Function of Insulin-making Cells
锻炼促进胰岛制造细胞功能
NEW YORK (Reuters Health) - Sedentary older people at risk of developing diabetes showed significant improvement in the function of their insulin-making beta cells after just one week of exercise, University of Michigan researchers found.
纽约(路透健康)密西根州大学研究发现,惯于久坐的老人,只要锻炼一个星期,出现危险的糖尿病人,制造胰岛beta细胞的功能明显改善。
Beta cell function is known to decline with age, although it is not clear why, Drs. Cathie J. Bloem and Annette M. Chang explain in the Journal of Clinical Endocrinology and Metabolism.
Cathie J. Bloem and Annette M. Chang 在临床内分泌和代谢杂志上解释,现已知道,年龄增长,Beta 细胞功能减退,虽然,还不知道什么原因
As people age, they may also become less sensitive to the blood sugar-regulating effects of insulin and develop impaired insulin secretion, the researchers add. And while short-term exercise boosts insulin sensitivity, it has not been clear how it might affect beta cell function.
研究人员又说,人老了,对胰岛素调节血糖的效果不敏感,胰岛素分泌受损。短时间的锻炼可以提高胰岛素的敏感性,原因还不清楚
To investigate, Bloem and Chang had 12 sedentary individuals aged 60 and older perform an hour-long workout every day for a week. The exercise sessions, consisting of stints on a treadmill, exercise bike and cross-training machine, required study participants to work out at 60 percent to 70 percent of their maximum heart rate capacity.
Bloem and Chang调查了12个惯于久坐的60岁以上的老人 ,一个星期每天锻炼长达一个小时。内容包括,踏车,自行车,交叉训练机,要求参加者保持最大心功率的60%到70%。
After the exercise period, study participants' sensitivity to insulin had increased by 53 percent, on average, while a measure of beta cell function called the disposition index had risen by 28 percent. However there were no changes in their fat mass, levels of fat in the blood, or other factors that might explain the effect of exercise on beta cells.
锻炼以后,参加者对胰岛素的敏感平均增加53%,而一项测定beta细胞功能的称作调节指数增加28%。然而,脂肪组织,血液脂肪水平,其他可以说明锻炼对beta细胞产生影响的因素,没有改变
\"Longer-term exercise training studies are required and are currently in progress to evaluate further exercise training effects on beta cell function in age-related glucose intolerance,\" the researchers note.
研究人员指出“需要对长期锻炼训练的研究,进一步评估,更多的锻炼训练,对葡萄糖耐量有关的老年人,beta细胞功能的影响“
SOURCE: Journal of Clinical Endocrinology and Metabolism, February 2008.
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