嗜烟者服用维生素E可能会增加患结核的风险

ewenwen2007

Vitamin E use may raise tuberculosis risk in heavy smokers
NEW YORK (Reuters Health) - The use of vitamin E supplements appears to increase the risk of tuberculosis in some middle-aged smokers, according to a study in the British Journal of Nutrition.
纽约（路透社健康信息）-----根据英国营养杂志报道的一个研究认为，补充维生素E可能会增加一些中年吸烟者患结核的风险。

In the overall analysis, vitamin E use did not affect the odds of tuberculosis in smokers. In people who smoked at least 20 cigarettes per day and consumed diets high in vitamin C, however, vitamin E supplements more than doubled the risk.
总的来说，补充维生素E不影响吸烟者患结核的机会。然而，对于每天吸烟至少20支以上，进食含维生素C丰富的食物、补充维生素E则会增加超过2倍的患结核风险。

Vitamin E is a widely used dietary supplement believed to enhance immune function, note authors Dr. Harri Hemila and Dr. Jaakko Kaprio. However, trials in human subjects have shown unpredictable effects of vitamin E on various infectious diseases.
Harri Hemila和Jaakko Kaprio博士说，维生素E被认为可以提高免疫力而被广泛使用。然而，临床试验显示维生素E对多种感染性疾病产生不可预测的影响。

To examine the impact of vitamin E use on the risk of tuberculosis, the two researchers from the University of Helsinki in Finland analyzed data from the ATBC (Alpha-Tocopherol, Beta-Carotene Cancer Prevention) Study.
来自芬兰赫尔辛基大学的两位研究人员，为了检测维生素E使用对患结核的风险，分析了从ATBS(Alpha-Tocopherol, Beta-Carotene Cancer Prevention)研究获得的数据。

The study participants were 29,023 male smokers, ages 50 to 69 years, who were randomly assigned to take daily supplements containing vitamin E, beta-carotene, vitamin E plus beta-carotene, or inactive placebo.
被研究的对象有29023名男性吸烟者，年龄从50到69对，他们被随机分到每天补充维生素E组，每天补充维生素E+beta胡萝卜素组，和补充安慰剂组。

During a follow-up period of around 6 years, 174 cases of tuberculosis were diagnosed. Overall, neither vitamin E nor beta-carotene supplements affected the risk of tuberculosis.
在长达6年的随访中，总共出现了174例结核病例，维生素E和beta胡萝卜素都没有影响患结核的风险。

However, as noted, the combination of smoking 20 or more cigarettes per day and consuming a diet rich in vitamin C and vitamin E supplements more than doubled the risk of tuberculosis. Further analysis showed that the increased risk was restricted to the first year after vitamin E supplementation began.
然而，正如前面提示的一样，对于每天吸烟至少20支以上，合并进食含维生素C丰富的食物、补充维生素E则会增加超过2倍的患结核风险。进一步的分析表明，患结核的风险的增加局限在开始服用维生素E后的第一年。

\"Although vitamin E may be beneficial in restricted population groups, those groups are poorly defined so far,\" Hemila and Kaprio point out.
Hemila 和Kaprio博士指出：“虽然维生素E可能对某些人群有用，但是对于每天吸烟至少20支以上的人群来说则是不利的。”

\"The consumption of vitamin E supplements by the general population should be discouraged because there is evidence of harm for some people,\" they conclude.
他们认为：“不建议普通人群补充维生素E，因为有证据表明补充维生素E会对某些人产生不利影响。”