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[【学科前沿】] 研究发现抑郁和卒中风险没有关联

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发表于 2008-3-19 07:04:28 | 显示全部楼层 |阅读模式
Study finds no depression link to stroke risk
LONDON (Reuters) - People who have had strokes are prone to depression, but a large, new study published on Monday said the psychological condition does not appear to raise the risk of stroke.
伦敦(路透社)-卒中患者经常抑郁,但在周一发表的一项大规模的新的研究结果表明,精神状况并不增加卒中风险。
Instead, the study said high degrees of psychological distress -- marked by anxiety and problems with emotional control -- seemed to increase the risk, the British researchers reported in the journal Neurology.
相反,英国研究者在神经学杂志上发表的该项研究结果显示,以情绪克制产生的焦虑和情感问题为特征的高度心理痛苦则会增加卒中风险。
\"A diagnosis of major depressive disorder was not important for predicting future stroke,\" said Paul Surtees, a clinical psychologist at the University of Cambridge, who led the study.
“抑郁障碍的诊断对于预测日后的卒中没有意义。”领导该项研究的剑桥大学的临床心理学家Paul Surtees如是说。
Strokes, which occur when blood flow to the brain is blocked, can kill brain tissue and are one of the worldwide leading causes of death and permanent disability. Treatments include blood thinning drugs and attempts to lower cholesterol.
发生在脑部血流阻断时的卒中可能杀伤脑组织,并且在世界范围内都是死亡和永久性致残的主要原因之一。治疗手段包括服用抗凝血药物和降低胆固醇。
Previous studies have shown that strokes often lead to depression but the evidence has been mixed when it comes to whether depression causes strokes.
先前的研究结果表明,卒中通常导致抑郁,但在抑郁是否导致卒中方面,证据被混淆了。
Surtees and his colleagues studied more than 20,000 people aged 41 to 80 over an eight-and-a-half-year period to see if they could find a link between depression and stroke.
Surtees 和他的同事们研究了超过20,000例年龄在41岁至80岁之间的病人,历时8年半多,旨在弄清抑郁和卒中之间的关系。
During this time nearly 600 people in the study suffered a stroke, 28 percent of them fatal. After factoring for known risk factors such as smoking, high blood pressure, obesity and family history, they found no significant link between depression and stroke.
在此期间,近600人患上了卒中,28%是致命的。抛开已知的风险因素吸烟、高血压、肥胖和家族史,研究者发现在抑郁和卒中二者间并没有密切的联系。
Instead, it seems that psychological distress plays a greater role. The most distressed people had a 40 percent higher stroke risk, Surtees said.
然而,研究显示心理痛苦扮演着重要的角色。Surtees说,最痛苦的人群比其他人群患卒中的风险高出40%。
\"The more distressed you were the greater the risk,\" Surtees said in a telephone interview.
你越痛苦,患疾病的风险越大,Surtees在电话采访中说。
The next step is to investigate exactly how psychological distress may lead to stroke, he added. The findings were similar for both men and women.
他还补充道,下一步研究是弄清心理痛苦如何导致卒中。该项研究不存在性别差异。
Distress may be a marker of other differences or indicate people having a tough time dealing with stressful situations, which may elevate their stroke risk, Surtees said.
Surtees说,心理痛苦可能表现为一些其他的情绪变化或者表明人正处在应激状态下经历一段艰难的时刻,这些可能增加卒中的风险
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