Drug Discovery and Development, Drug Discovery

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Hardcover: 456 pages
Publisher: Wiley-Interscience (June 16, 2006)
Language: English
ISBN: 0471398489
Product Dimensions: 10.1 x 7.3 x 1.1 inches

This two volume set provides a comprehensive account of the entire sequence of operations involved in discovering a drug through the actual delivery of the drug to clinicians and medical practitioners.
Includes case studies of the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil)
Discusses the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer
Contains chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics
The first volume of this set thoroughly describes conceptualizing a drug, creating a library of candidates for testing, screening those candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and revising the drug as necessary

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