宫颈癌术后的再发率高于常人两倍

Twice The Risk Of Cervical Cancer Despite Operation
宫颈癌术后的再发率高于常人两倍

Women who have had severe cell changes in the cervix and who have been operated on for them run twice the risk of developing cancer later in life, compared with other women. This is shown by research from the Sahlgrenska Academy in Gothenburg Sweeden that is now being published in British Medical Journal.
子宫颈细胞存在严重病变的妇女对比其他妇女在晚年行手术治疗癌症的风险增高一倍。Sahlgrenska学会的研究显示了这项在英国医学杂志发表的报道。

Swedish women are regularly called in for cell tests. In cases where severe changes in cells are discovered, the outer layer of the portio vaginalis is removed in an operation. Annually some 10,000 women in Sweden undergo this operation for cell changes in the cervix. If the cell changes are left untreated, there is a great risk of developing cervical cancer or vaginal cancer.
瑞典妇女常规要求进行细胞检测。在发现细胞有严重病变的病例中，需在手术中切除阴道外层组织。每年在瑞典有10,000例妇女行子宫颈手术，如发生病变的细胞未能得到治疗，则发生宫颈癌或阴道癌的风险较大。

But despite this operation and subsequent monitoring, these women still face 2.5 times the risk of developing cervical cancer or vaginal cancer compared with other women. This is shown in a Swedish study now being published in British Medical Journal.
尽管手术后进行随访，但这些妇女对比其他妇女仍有发生宫颈癌或阴道癌2.5倍的风险。这项瑞典的研究在英国医学杂志发表。

\"It is remarkable that the risk of cancer continues to be elevated even though the sections of the tissue where cervical cancer usually starts have been removed,\" says the study's lead author, Bjorn Strander, a doctoral candidate at the Sahgrenska Academy and chief physician at the Oncology Center for the Western Sweden health care region.
这项研究领导者Bjorn Strander说到“这些切除宫颈癌组织切片提示宫颈癌发生率明显提高。”

The researchers have been able to monitor women for more than 25 years after treatment and have found that the risk does not decline substantially after a long period. The elevated risk was greatest among women who were over the age of fifty when they underwent treatment for the cell changes. \"The treatments are successful since only about one percent of these women develop cancer, but it appears that women have not been monitored carefully enough with cell samples and not long enough after their treatment,\" says Bjorn Strander.
研究人员已随访大于25岁治疗后的妇女并发现这种风险在远期内并无实质上地降低。在50 岁以上因宫颈组织细胞病变行治疗后再发的风险性增高。Bjorn Strander提到“这种治疗是成功的因为只有1%患者发展为癌症，但治疗后似乎妇女并未进行足够细胞样本以及时期的随访。”

He therefore feels that it is important to review the special follow up programs that are offered following treatment for cell changes.
他认为对于因细胞病变治疗而进行特定的随访是重要的。

The study was carried out with the aid of the Swedish Cancer Register. This register includes severe cell changes that have not developed into cancer. A total of 132 493 women who have been treated for such cell changes could be followed for an average of 17 years, some of them as long as 40 years.
这项研究由瑞典癌症机构赞助。纳入病例包括宫颈细胞病变但未发展为癌症患者，总计132 493妇女治疗后随访平均为17年，一些患者甚至随访了40年。

\"Thanks to well-managed and comprehensive registers, we in Sweden can perform epidemiological studies and uncover interesting results that would not be possible in most other countries. They help Sweden maintain its prominent position in medical research,\" says Par Sparen, professor of medical epidemiology at the Karolinska Institute, and co-author of the study.
Par Sparen 说到“由于管理优良以及纳入病例的全面，我们在瑞典能进行流行病学研究并揭示了有趣的结果，而此在大多数其他国家并不可能实现。其将有助于瑞典人在医疗界中保持它的重要低位。”

The study will be included in Bjorn Strander's doctoral dissertation, to be submitted in January at the Sahlgrenska Academy. The dissertation is about improving the protection against cervical cancer in Sweden.
Bjorn Strander的博士论文内包含了这项研究，其于1月已经提交给了Sahlgrenska协会。这篇论文是有关于抑制宫颈癌的改善。