低脂饮食可降低卵巢癌患病风险

Low-fat diet possibly linked to lower risk of ovarian cancer
低脂饮食可降低卵巢癌患病风险
A low-fat diet may decrease the risk of ovarian cancer in postmenopausal women, according to a study published online October 9 in the Journal of the National Cancer Institute.
国家癌症学会杂志上的一项研究表明，低脂饮食可降低绝经妇女卵巢癌的患病风险。
Previous reports from the Women’s Health Initiative Dietary Modification Randomized Controlled Trial examined the effect of a low-fat diet on the risk of breast and colorectal cancer in postmenopausal women, but it was not yet known whether the same diet would alter ovarian cancer risk.
以前妇女健康与饮食控制实验报道了，低脂饮食对绝经后妇女乳腺癌和直肠癌患病风险的影响，但是并不知道这种饮食是否能改变卵巢癌患病风险。
Ross Prentice, Ph.D., of Fred Hutchison Cancer Research Center in Seattle and colleagues analyzed data from the dietary modification trial to see if the changes in the women’s diets decreased the risk of ovarian and endometrial cancer and invasive cancers overall. In the trial, nearly 20,000 women were randomly assigned to the diet modification group and almost 30,000 women ate their normal diet. The women participating in the diet were asked to reduce their fat intake to 20 percent of their overall diet, as well as eat at least five serving of fruits and vegetables a day and at least six servings of whole grains. They were followed for an average of eight years.
西雅图癌症研究中心Ross Prentice博士和同事们分析了饮食调整实验的数据，以判断改变妇女的饮食能否降低乳腺癌、子宫内膜癌及所有癌症的患病风险。实验中，随机选取了20，000妇女在饮食调整组，30，000在正常饮食组。饮食调整组的妇女要求减少脂肪摄入总量的20%，每天至少吃五分蔬菜水果及六分谷物。平均随访了八年。
The risk of ovarian cancer was similar in the two groups for the first four years of follow-up, but it was reduced in the dieting group during the following four years. Women who had the highest fat intake before the trial saw the greatest reduction in risk. There was no difference in endometrial cancer risk between the two groups, but a trend toward a reduction in invasive cancers overall was suggested in the dieting group. It was not, however, statistically significant.
在随访的前四年里两组的卵巢癌患病风险相似，但在后四年里饮食调整组的患病风险降低了。实验前脂肪摄入量越多的妇女实验后患病风险降的越低。两组子宫内膜癌的患病风险没有差异，但在饮食调整组所有癌症的患病风险都有降低的趋势，但是没有统计学意义。
“Ongoing …follow-up of trial participants may provide additional valuable assessment of the effects of a low-fat dietary pattern on these and other cancer incidence rates,” the authors write.
作者说：“随着实验的继续，实验参与者可能将为我们提供更多有关低脂饮食对卵巢癌及其他癌症发病率影响的资料。”

编译整理：（427字）
低脂饮食可降低卵巢癌患病风险

国家癌症学会杂志上的一项研究表明，低脂饮食可降低绝经妇女卵巢癌的患病风险。以前妇女健康与饮食控制实验报道了，低脂饮食对绝经后妇女乳腺癌和直肠癌患病风险的影响，但是并不知道这种饮食是否能改变卵巢癌患病风险。
西雅图癌症研究中心Ross Prentice博士和同事们分析了饮食调整实验的数据，以判断改变妇女的饮食能否降低乳腺癌、子宫内膜癌及所有癌症的患病风险。实验中，随机选取了20，000妇女在饮食调整组，30，000在正常饮食组。饮食调整组的妇女要求减少脂肪摄入总量的20%，每天至少吃五分蔬菜水果及六分谷物。平均随访了八年。
在随访的前四年里两组的卵巢癌患病风险相似，但在后四年里饮食调整组的患病风险降低了。实验前脂肪摄入量越多的妇女实验后患病风险降的越低。两组子宫内膜癌的患病风险没有差异，但在饮食调整组所有癌症的患病风险都有降低的趋势，但是没有统计学意义。作者说：“随着实验的继续，实验参与者可能将为我们提供更多有关低脂饮食对卵巢癌及其他癌症发病率影响的资料。”