预测肺癌存活率新方法

New method for predicting lung cancer survival
预测肺癌存活率的新方法

BEIJING, Sept. 3 (Xinhuanet) -- A thorough review of a decades-old method used to predict lung cancer survival means thousands more patients each year could be offered surgery or more aggressive therapy -- such as chemotherapy -- under a new system that classifies many tumors as more treatable.
新华社北京9月3日电——研究人员对一项实行了几十年之久的预测肺癌存活率的旧方法进行了彻底检讨，新方案将很多肿瘤划分为可治疗类，意味着每年接受手术或更积极的治疗如化疗的患者将增加千余例。

The new guidance was presented Saturday at a conference of lung cancer specialists in Seoul, South Korea. It is expected to be adopted by policy-making groups in the next year.
上周六，新方案在韩国汉城的肺癌专家会议上颁布，预计明年通过决策小组审议。

\"There will clearly be shifting of patients from categories not operable to operable\" — as many as 10,000 a year in the United States, said Dr. David Johnson, a lung cancer specialist at Vanderbilt University in Nashville, Tenn. He reviewed the plan, which was partly published in a medical journal recently.
新方案的部分内容刊登在最近的医学杂志上，田纳西纳什维尔范德比尔特大学的肺癌专家David Johnson阅读后称，很显然，新指导将很多患者从不可治疗类归为可治疗类，仅在美国，这一数目就高达每年1 0,000例。

Lung cancer is the world's No. 1 cancer killer, claiming 1.3 million lives each year. In the United States, 213,380 new cases and 160,390 deaths from the disease are expected this year. Nearly 60 percent of people die within one year of diagnosis, and nearly 75 percent die within two years, American Cancer Society statistics show.
肺癌是全球头号癌症杀手，每年夺去130万人的生命。预计今年美国将有213380例新发病例，并有16.039万人死于肺癌。美国癌症协会的统计表明，近60 ％患者诊断一年内死亡，有近75 ％ 在两年内死亡。

The current system, based on a tumors size and how far it has spread, was developd from about 5,000 tumor samples from University of Texas M.D. Anderson Cancer Center in Houston decades ago — before improved scanning technology was available to evaluate a cancer's spread.
现行方案是几十年前根据来自休斯顿德克萨斯大学M.D.安德森癌症中心的5000例肿瘤样本制定的，它以肿瘤体积及扩散程度为基础，那时还缺乏评估癌症扩散的有效扫描技术。

The new plan is based on 100,000 tumor samples from around the world including Asia, where lung cancer rates are projected to climb because of trends in smoking, unhealthy lifestyles and aging populations.
而新方案基于来自包括亚洲在内世界各地的10万例肿瘤样本。因为吸烟倾向、生活方式不健康及人口老龄化，亚洲的肺癌发病率呈上升趋势。

Dr. Peter Goldstraw, a surgeon at the Royal Brompton Hospital in London, led the project, and Canadian scientists independently validated the recommended changes by comparing survival across geographic regions.
伦敦皇家Brompton医院的外科医生 Peter Goldstraw博士主持了这一项目，加拿大研究人员通过比较不同地域肺癌存活率，独立验证了方案中的建议变动。

Among the changes: creating more sub-stages for tumor size, reassigning some large tumors to a more advanced stage, reclassifying tumors that have spread into the fluid surrounding the lung, and recognizing that spread to certain lymph nodes is more dangerous than its spread to others.
方案变动包括，对肿瘤体积进一步分级，将一些大型肿瘤列入晚期，对已扩散到肺部周围液体的肿瘤重新分类，并认定肿瘤扩散至某些特定淋巴结比扩散至其他淋巴结更危险。

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编译

预测肺癌存活率的新方法

新华社北京9月3日报道，研究人员对一项实行了几十年之久的预测肺癌存活率的旧方法进行了彻底检讨，新方案将很多肿瘤划分为可治疗类，意味着每年接受手术或更积极的治疗如化疗的患者将增加千余例。
现行方案是几十年前根据来自M.D.安德森癌症中心的5000例肿瘤样本制定的，以肿瘤体积及扩散程度为基础，那时还缺乏评估癌症扩散的有效扫描技术。
而新方案的10万例肿瘤样本来自包括亚洲在内的世界各地。因为吸烟倾向、生活方式不健康及人口老龄化，亚洲的肺癌发病率呈上升趋势。
伦敦皇家Brompton医院的Peter Goldstraw博士主持了这一项目，加拿大研究人员通过比较不同地域肺癌存活率，独立验证了方案中的建议变动。
方案变动包括，对肿瘤体积进一步分级，将一些大型肿瘤列入晚期，对已扩散到肺部周围液体的肿瘤重新分类，并认定肿瘤扩散至某些特定淋巴结比扩散至其他淋巴结更危险。
新方案的部分内容刊登在最近的医学杂志上，专家称，新方案将很多患者从不可治疗类归为可治疗类，仅在美国就高达每年1 0,000例。
新方案于上周六在韩国汉城的肺癌专家会议上颁布，预计明年通过决策小组审议。