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[【学科前沿】] 减肥手术降低死亡率

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发表于 2007-8-28 00:45:57 | 显示全部楼层 |阅读模式
Weight-Loss Surgery Cuts Death Rate
Posted by Jacob Goldstein
减肥手术降低死亡率

Weight-loss surgery cuts the mortality rate for obese people, according to two studies published in this week’s New England Journal of Medicine. The stomach surgery has clearly been shown as a way to help people lose weight, but the question of whether it extends life had not clearly been answered.
根据这周《新英格兰医学期刊》(NEJM)发表的两项研究,减肥手术使肥胖人群的死亡率下降。胃部手术显然可以让人减肥,但是它是否可以延长生命以前并没有定论。

The author of an NEJM editorial that accompanied the research told the WSJ that the studies are analogous to “the statin trials that showed the drugs reduced death rates and not just cholesterol” — trials that prompted sales of the drugs to skyrocket. The surgery already has been gaining popularity quickly, and is now being studied as a possible treatment for diabetes.
NEJM上,伴随这项研究的一篇社论的作者在华尔街日报上称,这两项研究和“表明他汀类药物不仅可以降低胆固醇,也可以降低死亡率的试验”很相似。——他汀试验的结果出来以后,使他汀类药的销量猛增。减肥手术本来就很快地流行着,现在它被作为糖尿病的可能治疗手段来研究。

One of the new studies, conducted in Sweden, randomly assigned just over 4,000 people to either surgery or conventional treatment. During a follow-up period of about 11 years, those who received surgery were 29% less likely to die than those who received conventional treatment.
其中的一项研究在瑞典进行,先将4000多个试验对象随机地分为手术组和传统治疗组。在约11年的随访时间里,手术组对象的死亡率比传统治疗组对象的死亡率低29%。

The other study did not randomly assign people to one group or another, but compared roughly 8,000 people who had surgery with an identical number of people of similar age, sex, and body-mass index who did not have surgery. During a follow-up period of about seven years, those who had surgery were 40% less likely to die than those who did not. The studies are online here and here.
另一项试验没有随机地将对象分组,而是将大约8000个做过手术的对象与相同人数的、没有做手术、年龄、性别、体重指数相似的对象进行了比较。在约7年的随访时间里,手术组对象的死亡率比未经手术组的死亡率低了40%。这些研究在网上随处可以找到。

编译:(字数 262字)
减肥手术降低死亡率

《新英格兰医学期刊》本周载文,两项研究表明减肥手术使肥胖人群的死亡率下降。
这次研究将使减肥手术更加流行,因为现在它已经是糖尿病的可能治疗手段。
一项研究在瑞典进行,先将4000多个试验对象随机地分为手术组和传统治疗组。在约11年的随访时间里,手术组对象的死亡率比传统治疗组对象的死亡率低29%。
另一项试验没有随机地将对象分组,先选择大约8000个做过手术的对象组成手术组,再逐个配给相同人数的,没有做过手术,年龄、性别、体重指数相似的对象组成未经手术组。在约7年的随访时间里,手术组对象的死亡率比未经手术组的死亡率低了40%。
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发表于 2007-8-28 11:44:57 | 显示全部楼层
减肥手术降低死亡率
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