Chemokine Biology: Basic Research and Clinical Application: Vol. 2: Pathophys

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Publisher:  Birkh鋟ser Basel
Number Of Pages:  168
Publication Date:  2007-05-21
Sales Rank:  329319
ISBN / ASIN:  3764371951
EAN:  9783764371951
Binding:  Hardcover
Manufacturer:  Birkh鋟ser Basel
Studio:  Birkh鋟ser Basel
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Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role

in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens,

invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various

diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV.
Volume 2 of this two-volume set discusses the pathophysiology of chemokines. It is divided into two parts: a) chemokines in animal disease models, and b)

chemokines as drug targets. Together with volume 1, which discusses the immunobiology of chemokines, both volumes give a comprehensive overview of chemokine

biology.

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