Infectious Disease Clinics of North America MARCH 2007 HIV/AIDS

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The AIDS pandemic has had a remarkable course during the more than
quarter century since it was first detected. Tens of millions of individuals
have died because the complications of HIV infection, and at present more
than 40 million people across the planet are living with HIV. As of next
year, it is expected that there will be an additional 3 million deaths and
probably 5 million new infections. Nonetheless, the past few years have seen
remarkable advances in antiretroviral chemotherapy. Highly active antiretroviral
therapy has resulted in the ability of many people living with HIV
to lead highly productive lives, with pill burdens as low as one pill taken
once a day and with minimal side effects. Not everyone living with HIV
who has access to therapy has an uncomplicated course, and there are concerns
about chronic, metabolic, immunologic effects of the therapies themselves
as well as concerns about the effects of chronic HIV infection. At the
same time, the ultimate moral imperative is to avoid unnecessary deaths and
morbidity by making the benefits of antiretroviral therapy available to the
largest number of people throughout the world as soon as possible.

Global Epidemiology of HIV-AIDS

Diagnosis and Management of Acute HIV Infection

Primary Care Issues for HIV-Infected Patients

Antiretroviral Management of Treatment-Naive Patients

Approach to the Treatment-Experienced Patient

Management of Antiretroviral Treatment–Related Complications

Special Care Issues of Women Living with HIV-AIDS

Clinical Care of the HIV-Infected Drug User

Behavioral Aspects of HIV Care: Adherence, Depression, Substance Use, and HIV-Transmission Behaviors

HIV Vaccine Efficacy Trials: Towards the Future of HIV Prevention

The Future of HIV Prevention: Prospects for an Effective Anti-HIV Microbicide

The Future of HIV Prevention: Control of Sexually Transmitted Infections and Circumcision Interventions

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