农药残留手册（英文版）

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农药残留手册（英文版），pdf格式，132页

MULTICLASS MRMS: CONCEPT AND APPLICATION
Pesticide multiresidue methods (MRMs) are capable of simultaneously determin-ing more than one residue in a single analysis; this multiresidue capability is provided by a GLC or HPLC determinative step that separates residues from one another before detection. The MRM concept is raised to a higher dimension when a single extract is examined with more than one chromatographic determinative step, each providing coverage of residues in a different class, e.g., chlorinated hydrocarbons, organophosphates, and carbamates. PAM I refers to these broad scope methods as “multiclass MRMs.”
A multiclass MRM is potentially capable of determining any residue extracted by its extraction step; PAM I multiclass MRMs extract residues with organic solvents known to remove most nonionic residues from food commodities. Each determinative step in a multiclass MRM provides coverage for a particular group of residues in the extract, and each cleanup step is designed to purify the extract sufficiently to permit accurate determination. A multiclass MRM scheme can be expanded continually as new technologies are developed and adapted.
This introductory section presents a recommended approach to application of multiclass MRMs and background information with which any analyst using such methods should be familiar.