生命科学最前沿

lmj2029

是了解生命过程的本质,了解世界生命科学的最前沿的一个窗口.
Related Resources:
Editorial Guides
• E. M. Adler, N. R. Gough, L. B. Ray, 2004: Signaling breakthroughs
of the year. Sci. STKE 2005, eg1 (2005).
• E. M. Adler, N. R. Gough, L. B. Ray, 2003: Signaling breakthroughs
of the year. Sci. STKE 2004, eg1 (2004).
• E. M. Adler, N. R. Gough, L. B. Ray, 2002: Signaling breakthroughs
of the year. Sci. STKE 2003, eg1 (2003).
• N. R. Gough, E. M. Adler, Focus issue: RNA, a multifunctional
molecule. Sci. STKE 2005, eg8 (2005).
This Week in STKE
• The message is the messenger. Sci. STKE 2005, tw332
(2005).
• Zipping up targeting and translation. Sci. STKE 2005, tw422
(2005).
• miRNA contributes to neuronal morphogenesis. Sci. STKE
2005, tw406 (2005).
• Stargazin, traffic cop and gate keeper. Sci. STKE 2005,
tw239 (2005).
• Dissecting dopamine’s behavioral effects. Sci. STKE 2005,
tw227 (2005).
• A pathway to schizophrenia? Sci. STKE 2005, tw419 (2005).
• Redistribution of STIM proteins to the peripheral structures
in store-operated calcium influx. Sci. STKE 2005, tw262
(2005).
• A constitutively active JAK2 mutant underlies polycythemia
vera. Sci. STKE 2005, tw165 (2005).
• Antiviral signaling from the mitochondria. Sci. STKE 2005,
tw324 (2005).
• Modeling signaling networks. Sci. STKE 2005, tw157
(2005).
• A model of regulation. Sci. STKE 2005, tw378 (2005).
Connections Maps
• Connections Map Database, Sci. STKE, http://stke.
sciencemag.org/cm/.
Perspectives
• G. Balázsi, Z. N. Oltvai, Sensing your surroundings: How
transcription-regulatory networks of the cell discern environmental
signals. Sci. STKE 2005, pe20 (2005).
• C. Hisatsune, K. Mikoshiba, Novel compartment implicated
in calcium signaling—Is it an “induced coupling domain”?
Sci. STKE 2005, pe53 (2005).
• W. G. Kaelin Jr., Gleevec: Prototype or outlier? Sci. STKE
2004, pe12 (2004).
• H. K. Manji, I. I. Gottesman, T. D. Gould, Signal transduction
and genes-to-behaviors pathways in psychiatric
diseases. Sci. STKE 2003, pe49 (2003).
• J. P. Morris IV, M. T. McManus, Slowing down the ras lane:
miRNAs as tumor suppressors? Sci. STKE 2005, pe41
(2005).
• A. Pollack, Coactivation of D1 and D2 dopamine receptors:
In marriage, a case of his, hers, and theirs. Sci. STKE 2004,
pe50 (2004).
• E. E. Schadt, A. Sachs, S. Friend, Embracing complexity,
inching closer to reality. Sci. STKE 2005, pe40 (2005).
• H. Vaucheret, MicroRNA-dependent trans-acting siRNA
production. Sci. STKE 2005, pe43 (2005).
• E. Werner, Meeting report: The future and limits of systems
biology. Sci. STKE 2005, pe16 (2005).
Review
• D. S. Charney, H. K. Manji, Life stress, genes, and depression:
Multiple pathways lead to increased risk and new opportunities
for intervention. Sci. STKE 2004, re5 (2004).
Protocol
• D. Pe’er, Bayesian network analysis of signaling networks:
A primer. Sci. STKE 2005, pl4 (2005).
Teaching Resources
• R. D. Blitzer, Long-term potentiation: Mechanisms of induction
and maintenance. Sci. STKE 2005, tr26 (2005).
[Slides (http://stke.sciencemag.org/cgi/content/full/
sigtrans;2005/309/tr26/DC1)]
• A. Contractor, S. F. Heinemann, AMPA receptor cycling in
the synapse. Sci. STKE 2004, tr7 (2005). [Resource Details
(http://stke.sciencemag.org/cgi/content/full/sigtrans;
2004/255/tr7/DC1)]
• K. S. Kosik, A. M. Krichevsky, A model for local regulation
of translation near active synapses. Sci. STKE 2005, tr25
(2005). [Animation (http://stke.sciencemag.org/cgi/content/
full/sigtrans;2005/300/tr25/DC1)]
E D I TORIAL GUIDE[p:1]