不定期推出生物医学系列图书

josephe

Advanced Imaging in Biology and Medicine
Technology, Software Environments, Applications
Sensen, Christoph W.; Hallgrímsson, Benedikt (Eds.)
2009, XII, 445 p. 164 illus., 103 in color., Hardcover
ISBN: 978-3-540-68992-8
PDF 61 Mb


Description: This is the first comprehensive book, which covers the major themes of the rapidly emerging field of advanced imaging in Biology and Medicine. The analysis of phenotypic information is increasing in importance in biological research. This is because the growth of information and the increasing use of sophisticated models for understanding complex biological systems is leading to an increased need to apply multifactorial models in which subtle phenotypic outcomes often need to be assessed to compare the effects of multiple genetic or pharmaceutical factors. Such applications will increasingly rely on multiple imaging modalities and will demand high throughput and standardized methods of data analysis. For this reason, a single volume that integrates the use of various imaging modalities with this perspective is timely and useful for a large segment of the biological community.

云之惑

有句话，我想对你说已经很久了！

你是个好人！

josephe

Gene Cloning and Manipulation
Author:Christopher Howe
Publisher: Cambridge University Press (2007)
Binding: Hardcover, 276 pages
pricer: $125.00
ISBN-10: 0521817935
deweydecimal: 572.86
edition: 2
PDF: 8M

editorialreviews
Now fully updated to reflect recent advances, this introduction provides a broad, but concise, coverage of recombinant DNA techniques. Emphasis is placed on the concepts underlying particular types of cloning vectors to aid understanding and to enable readers to devise suitable strategies for novel experimental situations. A series of 'real-life' biological problems are also presented to enable readers to assess their understanding of the material and to prepare for exams.

maobu

法律之窗版特邀楼主到法律版开个专帖。。。

云之惑

引用第3楼maobu于2009-03-18 19:17发表的 :
法律之窗版特邀楼主到法律版开个专帖。。。

你那不是已经有个特供了嘛！

josephe

引用第3楼maobu于2009-03-18 19:17发表的 :
法律之窗版特邀楼主到法律版开个专帖。。。

你那边啊？偶可不敢去。

brianleeeee才是行家里手。

josephe

RNAi: Design and Application (Methods in Molecular Biology)
Author:
Publisher: Humana Press (2008)
Binding: Hardcover, 270 pages
pricer: $99.50
ISBN-10: 1588298744
deweydecimal: 616
edition: 1
PDF:

editorial reviews

RNA interference (RNAi), in which RNA silences RNA, is the most recent discovery to revolutionize the study of biology. In RNAi: Design and Applications, leaders in the field contribute state-of-the-art, easy to follow methods and bench protocols designed for practical, everyday use of RNAi in biological research. Divided into two parts, this comprehensive volume covers fundamentals including designs of RNAi, biochemical assay protocols for the major components of RNAi, and study of potential off-target effects, followed by an extensive section covering various applications of RNAi in diverse model organisms and systems, from antiviral and anticancer applications to altering flower color in plants.

Cutting edge and clearly written, RNAi: Design and Applications enables a researcher with standard molecular biological training to perform major RNAi-related experiments and contribute to this revolutionary, growing field.

josephe

RNAi Advanced Methods
Author:Mart Latterich
Publisher: Taylor & Francis (2007)
Binding: Paperback, 138 pages
pricer: $76.95
ISBN-10: 0415409500
deweydecimal: 572.88
edition: 1
editorialreviews
One of the major recent discoveries in molecular and cellular biology is that small double-stranded RNA molecules selectively turn off gene expression in all types of cell, a phenomenon known as RNA silencing. This discovery led to the development of RNA interference (known as RNAi) as a powerful research tool in the functional study of individual genes and their products, and in functional genomics. In RNAi, specific small double-stranded RNA molecules (small interfering RNAs or siRNAs) are introduced into cells to selectively silence certain genes."RNAi "covers the basic concepts and mechanisms of RNAi, transfection of cells with siRNAs, the design and validation of RNAi reagents, RNAi techniques in different organisms, large-scale RNAi screening, applications of RNAi in drug discovery, and potential uses of RNAi as a therapeutic agent. A key feature of "RNAi" is the highlighting of the pitfalls that can occur and how to minimize them. The book also contains a complete list of abbreviations, as there are many confusing terms associated with RNAi.

josephe

Applied Cell and Molecular Biology for Engineers
Author:
Publisher: McGraw-Hill Professional (2007)
Binding: Hardcover, 326 pages
pricer: $115.00
ISBN-10: 0071472428
deweydecimal: 571.6
edition: 1
editorialreviews
A Guide to the Fundamentals and Latest Concepts of Molecular and Cell Biology


Bridging the gap between biology and engineering, Applied Cell and Molecular Biology for Engineers uses clear, straightforward language to introduce you to the cutting-edge concepts of molecular and cell biology.

Written by an international team of engineers and life scientists, this vital tool contains “clinical focus boxes” and “applications boxes” in each chapter to link biology and engineering in today's world. To help grasp complex material quickly and easily, a glossary is provided.

Applied Cell and Molecular Biology for Engineers features:

Clear descriptions of cell structures and functions
Detailed coverage of cellular communication
In-depth information on cellular energy conversion
Concise facts on information flow across generations
A succinct guide to the evolution of cells to organisms

josephe

Gene Knockout Protocols (Methods in Molecular Biology, 530)

With the completion of the mouse and human genome sequences, the functional characterization of every mammalian gene and the deciphering of their molecular interaction network has become the next major challenge, and the mouse genome provides a convenient and vital model for these studies. In "Gene Knockout Protocols, Second Edition", distinguished contributors with extensive experience in the gene targeting and mouse genetics fields reveal a comprehensive collection of step-by-step laboratory protocols. Emphasizing the many new mutagenesis techniques developed over the last seven years, the volume covers topics such as gene modification in ES cells, stem cell manipulation, the generation of genetically engineered mice, and mutant phenotype analysis. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain brief introductions to their respective subjects, lists of the necessary materials and reagents, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Fully updated and authoritative, "Gene Knockout Protocols, Second Edition" provides a unique collection of expert bench protocols certain to be a valuable resource for those just entering the field of gene targeting but also for all genetic researchers today.

josephe

Drug-Drug Interactions, Second Edition (Drugs and the Pharmaceutical Sciences)
Author:
Publisher: Informa HealthCare (2008)
Binding: Hardcover, 768 pages
pricer: $249.95
ISBN-10: 0849375932
deweydecimal: 615.7045
edition: 2
editorialreviews
Helping researchers predict drug interactions in a more accurate and effective manner, this comprehensive volume covers every critical aspect of metabolism-based drug-drug interactions, including preclinical, clinical, toxicological, regulatory, and marketing perspectives by renowned thought leaders in their respective fields. Thoroughly updated, the Second Edition reflects key developments in the field, including an improved understanding of the relationship between transporters and enzymes in drug metabolism and drug interactions. Formatted to benefit the reader, this source provides helpful case examples, representative enzyme systems, and computer-aided modeling, as well as 200 valuable tables, equations, drawings, and photographs to clarify key concepts.

woi55

誓把josephe的红旗插满论坛各个版面！

zhangyq

楼主发的书 都是相当前沿的，很高深，学习了，下来本研究一下，谢谢楼主

josephe

Membrane Proteomics: Methods and Protocols (Methods in Molecular Biology)
Author:
Publisher: Humana Press (2009)
Binding: Hardcover, 318 pages
pricer: $110.00
ISBN-10: 1603273093
deweydecimal: 570
edition: 1
editorialreviews

With the great cellular and therapeutic importance of plasma membrane proteins, unbiased technologies such as proteomics become even more vital as they have the power to define patterns of membrane protein expression characteristic of distinct states of cellular development, differentiation or disease, and thereby identify novel markers of, or targets for intervention in, disease. In Membrane Proteomics: Methods and Protocols, leading experts in the field compile a laboratory bench resource which provides a comprehensive toolkit of proven methods. The volume delves into various modifications to standard two-dimensional gel electrophoresis protocols as well as liquid chromatographic methods, protocols for the enrichment of diverse classes of plasma membrane proteins, in silico approaches, and cutting-edge techniques for quantitative membrane protein profiling. Written in the highly successful Methods in Molecular Biology? series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Comprehensive and easy-to-use, Membrane Proteomics: Methods and Protocols is an ideal guide for investigators wishing to apply state of the art membrane proteomic methodologies in their own research programs.

josephe

Transmembrane Signaling Protocols (Methods in Molecular Biology)
Author:
Publisher: Humana Press (2006)
Binding: Hardcover, 376 pages
pricer: $104.00
ISBN-10: 158829546X
deweydecimal: 571.74
edition: 2
editorialreviews
This fully updated and expanded second edition of Transmembrane Signaling Protocols demonstrates the use of such techniques as single cell imaging, bioluminecence resonance energy transfer, and global proteomics in the study of transmembrane signaling events. Highlights include the functional expression and genetic selection of mutant mammalian transmembrane receptors in yeast, real-time analysis of transmembrane receptor signaling in live cells, and bioluminescence energy transfer to monitor protein-protein interaction. Additional chapters use state-of-the-art methods to analyze gene expression and proteomic profiles related to transmembrane signaling events, as well as to genetically reconstitute bone marrow for the study of signal transduction ex vivo. The protocols follow the successful Methods in Molecular Biology? series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

josephe

Molecular Biomethods Handbook
Author:
Publisher: Humana Press (2008)
Binding: Hardcover, 1124 pages
pricer: $150.00
ISBN-10: 1603273700
deweydecimal: 612
edition: 2
editorialreviews

Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. Molecular Biomethods Handbook, 2nd Edition expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Part A of the book describes nucleic acid methods, such as gene expression profiling, microarray analysis and quantitative PCR. In Part B, protein and cell-based methods are outlined, in subjects ranging from protein engineering to high throughput screening. Written by a well-established panel of research scientists, Molecular Biomethods Handbook, 2nd Edition provides an up to date collection of methods used regularly in the authors’ own research programs. This book will prove to be an invaluable reference for those engaged in or entering the field of molecular biology, and will provide the necessary background for those interested in setting up and using the latest molecular

josephe

经典“圣经”，尽管出版已多年，依然是实验室之必备。


生命科学实验室的圣经——分子克隆实验指南（第三版）
【作　者】(美)J.萨姆布鲁克(Joseph Sambrook)，(美)D.W.拉塞尔(David W.Russell)著 黄培堂等译
【丛书名】现代生物技术译丛
【形态项】 979 ; 26cm
【出版项】 科学出版社 , 2002
【ISBN号】 7-03-010338-6 / Q523-33
【原书定价】 CNY168.00
【主题词】脱氧核糖核酸(学科: 重组 学科: 实验)脱氧核糖核酸 重组
【参考文献格式】(美)J.萨姆布鲁克(Joseph Sambrook)，(美)D.W.拉塞尔(David W.Russell)著 黄培堂等译. 分子克隆实验指南. 科学出版社, 2002.

《分子克隆实验指南》的前两版以其无克匹敌的声誉，在近20年的时间里一直被作为分子生物学实验的经典参考书。在第三版中，作者对图书内容进行了完全的升级，修订了实验的每条方案，增加了大量新的材料，拓宽了它涉及的领域，内容丰富而详细，使其具有用于学习遗传学、分子细胞生物学、发育生物学、微生物学、神经科学和免疫学等科学的重要指导和参考价值。本书具有先进性、实用性、权威性的特点，是生命科学实验室内当之无愧的“圣经”。


Molecular Cloning: A Laboratory Manual volume 1
Molecular Cloning: A Laboratory Manual volume 2
Molecular Cloning: A Laboratory Manual volume 3
Author:Joe Sambrook
Publisher: Cold Spring Harbor Laboratory Press (2001)
Binding: Paperback, 999 pages
pricer: $259.00
ISBN-10: 0879695773
deweydecimal: 572.8
edition: 3
editorialreviews
The first two editions of this manual have been mainstays of molecular biology for nearly twenty years, with an unrivalled reputation for reliability, accuracy, and clarity.

In this new edition, authors Joe Sambrook and David Russell have completely updated the book, revising every protocol and adding a mass of new material, to broaden its scope and maintain its unbeatable value for studies in genetics, molecular cell biology, developmental biology, microbiology, neuroscience, and immunology.

Handsomely redesigned and presented in new bindings of proven durability, this three-volume work is essential for everyone using today’s biomolecular techniques.

The opening chapters describe essential techniques, some well-established, some new, that are used every day in the best laboratories for isolating, analyzing and cloning DNA molecules, both large and small.

These are followed by chapters on cDNA cloning and exon trapping, amplification of DNA, generation and use of nucleic acid probes, mutagenesis, and DNA sequencing.

The concluding chapters deal with methods to screen expression libraries, express cloned genes in both prokaryotes and eukaryotic cells, analyze transcripts and proteins, and detect protein-protein interactions.

The Appendix is a compendium of reagents, vectors, media, technical suppliers, kits, electronic resources and other essential information.

As in earlier editions, this is the only manual that explains how to achieve success in cloning and provides a wealth of information about why techniques work, how they were first developed, and how they have evolved.

josephe

Apoptosis, Cell Signaling, and Human Diseases
Molecular Mechanisms, Volume 1
Molecular Mechanisms, Volume 2
Author:
Publisher: Humana Press (2007)
Binding: Hardcover, 384 pages
pricer: $145.00
ISBN-10: 1588296776
deweydecimal: 571.936
edition: 1
editorialreviews

Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 and 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases. These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology.

Volume 1 is divided into two sections: “Malignant Transformation and Metastasis” and “Molecular Basis of Disease Therapy.” Volume 2 follows a similar structure and is divided into sections entitled “Kinases and Phosphate” and “Molecular Basis of Cell Death.” All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.

josephe

microRNAs: From Basic Science to Disease Biology
Author:
Publisher: Cambridge University Press (2008)
Binding: Hardcover, 560 pages
pricer: $195.00
ISBN-10: 0521865980
deweydecimal: 660
edition: 1
editorialreviews
MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development.

Forewords by:
Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989
and
Victor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs

朝廷首辅

书是好书，对专业人士是宝贵的参考资料。