Proteoglycans: Structure, Biology, and Molecular Interactions

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Proteoglycans: Structure, Biology, and Molecular Interactions by Renato V. Iozzo (Editor)
Publisher: CRC; 1st edition (April 15, 2000) | ISBN-10: 0824703340 | PDF | 33 Mb | 422 pages

This groundbreaking reference offers a comprehensive, up-to-date review of the structure, biology, and molecular interactions of proteoglycans, consolidating into a single source the latest research using molecular, cellular, and animal systems. Details the role of heparan sulfate in modulating growth factors and morphogens! Containing over 1700 bibliographic citations to encourage continued study, Proteoglycans

explains the structure and biosynthesis of glycosaminoglycans
covers transmembrane proteoglycans and their emerging roles in signaling
examines the structure and function of hyaluronan and its receptors
describes the ways proteoglycans are catabolized in diseased and healthy tissues
discusses secretory granule proteoglycans and their modulation of immune response
details maintenance of corneal transparency and skin homeostasis
outlines genetic alterations of specifically encoded genes
highlights basement membrane proteoglycans and their role in filtration, angiogenesis, and tumor formation
considers cartilage proteoglycans in congenital and acquired diseases
reveals proteoglycans of the central nervous system
With contributions from more than 30 international authorities in their respective fields, Proteoglycans is a top-shelf reference for molecular, experimental, and cell biologists and biochemists; pathologists; geneticists; oncologists; hematologists; rheumatologists; infectious disease specialists; neurologists; pediatricians; and graduate and medical students in these disciplines.

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