Protein-Solvent Interactions

Table of Contents

Preface
Contributors
1 The New Paradigm for Protein Research 1
2 Solvent Interactions with Proteins as Revealed by X-Ray Crystallographic Studies 143
3 Protein Hydration and Glass Transition Behavior 191
4 Dielectric Studies of Protein Hydration 265
5 Protein Dynamics: Hydration, Temperature, and Solvent Viscosity Effects as Revealed by Rayleigh Scattering of Mossbauer Radiation 289
6 Proteins in Essentially Nonaqueous Environments 327
7 Solvent Viscosity Effect on Protein Dynamics: Updating the Concepts 343
8 Effect of Solvent on Protein Internal Dynamics: The Kinetics of Ligand Binding to Myoglobin 375
9 Solvent Effects on Protein Stability and Protein Association 387
10 Thermodynamic Mechanisms for Enthalpy-Entropy Compensation 421
11 Preferential Interactions of Water and Cosolvents with Proteins 445
12 Thermodynamic Nonideality and Protein Solvation 483
13 Molecular Basis for Protein Separations 521
Index 555
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