Metabonomics in Toxicity Assessment

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Metabonomics in Toxicity Assessment

By Donald G. Robertson, John Lindon, Jeremy K. Nicholson, Elaine Holmes

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Publisher: Informa Healthcare
Number Of Pages: 536
Publication Date: 2005-03-01
ISBN-10 / ASIN: 0824726650
ISBN-13 / EAN: 9780824726652
Binding: Hardcover

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Book Description:

Filling a gap in the literature, this reference provides comprehensive coverage of all aspects of metabonomics technology including analytical and biologic considerations, as well as sections on chemometrics-devoting entire chapters to critical topics such as biomarkers, metabolite identification, and the use of magic angle spinning for tissue metabonomics. It includes numerous examples illustrating strategies and techniques for the identification of endogenous and xenobiotic metabolites. Providing essential tools for the toxicologist utilizing metabonomic technologies, this guide presents a clear outline of the use of metabonomics in the safety assessment of new chemical entities. OTI #1 1963

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