本书适用于分子生物学、分子遗传学及相关课程,是从事生物遗传学、生物化学、细胞生物学、基础医学等专业人员进行科学研究的重要参考书。
20年前Benjamin Lewin 的Genes一书从根本上改变了当时分子生物学和分子遗传学的授课方法和体系,从而确立了该书在此领域毋容置疑的权威性,多年来一直是国外著名研究生院入学考试的指定参考书。
本书最新版本(第八版)对第七版内容进行了全面的修订,加入了最新的人类基因组内容。提供了完备的网络资源:www.ergito.com--- Includes a complete E-book with flash illustrations;随时升级,保证紧贴发展前沿;丰富的资源(Flash Illustrations/ Multiple Views/ Hyperlinks),提供全方位教学支持。
主要章节:
(NOTE: Every chapter opens with an Introduction and concludes with a Summary.)
I. GENES.
1. Genes are DNA.
2. The Interrupted Gene.
3. The Content of the Genome.
4. Clusters and Repeats.
II. PROTEINS.
5. Messenger RNA.
6. Protein Synthesis.
7. Using the Genetic Code.
8. Protein Localization.
III. GENE EXPRESSION.
9. Transcription.
10. The Operon.
11. Regulatory Circuits.
12. Phage Strategies.
IV. DNA.
13. The Replicon.
14. DNA Replication.
15. Recombination and Repair.
16. Transposons.
17. Retroviruses and Retroposons.
18. Rearrangement of DNA.
V. THE NUCLEUS.
19. Chromosomes.
20. Nucleosomes.
21. Promoters and Enhancers.
22. Activating Transcription.
23. Controlling Chromatin Structure.
24. RNA Splicing and Processing.
25. Catalytic RNA.
26. Immune Diversity.
VI. CELLS.
27. Protein Trafficking.
28. Signal Transduction.
29. Cell Cycle and Growth Regulation.
30. Oncogenes and Cancer.
31. Gradients, Cascades, and Signaling Pathways.