Vaccinia Virus and Poxvirology: Methods and Protocols (Methods in Molecular B

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Vaccinia Virus and Poxvirology: Methods and Protocols (Methods in Molecular Biology)
Publisher:  Humana Press
Number Of Pages:  416
Publication Date:  2004-04-19
Sales Rank:  1606537
ISBN / ASIN:  1588292290
EAN:  9781588292292
Binding:  Hardcover
Manufacturer:  Humana Press
Studio:  Humana Press


A comprehensive collection of cutting-edge methods to study and work with the vaccinia virus and other poxvirus gene transcriptions. These readily reproducible techniques can be used for the construction and characterization of recombinant viruses; for the study of poxvirus gene transcription and DNA replication; for the investigation of the binding, entry, and movement of the virus in host cells; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxviruses-the latter a critical ability given the important role of vaccinia virus in smallpox vaccination and their potential role as vaccine vectors directed against infectious agents and cancer.

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