DNA Repair Protocols (Methods in Molecular Biology)

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DNA Repair Protocols (Methods in Molecular Biology)
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Publisher:  Humana Press
Number Of Pages:  512
Publication Date:  2005-10-01
Sales Rank:  1962812
ISBN / ASIN:  1588295133
EAN:  9781588295132
Binding:  Hardcover
Manufacturer:  Humana Press
Studio:  Humana Press
Average Rating:  5
Total Reviews:  1



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Book Description:

This collection of readily reproducible techniques for repairing mammalian DNA contains fourteen entirely new chapters and many extensively revised chapters. The methods presented cover cytogenetic analysis, measuring the cellular response to ionizing radiation, detecting single-strand (nicks) and double-strand DNA breaks, detecting the presence of \"adducted\" bases in DNA, and preparing mismatch repair (MMR) plasmid substrates. Among the highlights are excellent coverage of both base excision repair (BER) and nucleotide excision repair (NER), useful assays for identifying and quantifying UV-induced DNA lesions and DNA breakage, gene therapy, environmental mutagenesis and cancer, and gene targeting.





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Date: 2000-05-01  Rating: 5
Review:
DNA Repair Protocols: Eukaryotic Systems

Personally I think \"DNA Repair Protocol: Eukaryotic Systems\" is a great academic book based on my over ten years of research experiences in Genetic Toxicology. This book provides detailed, step-by-step instructions for studying manifold aspects of the eukaryotic responses to genotoxic damage, including a lot of useful tips in handling all kinds of DNA repair experiments. Compared with Friedberg's textbook \"DNA Repair and Mutagenesis\", which comprehensively covers all fundamental knowledge about DNA damage, mutagenesis and DNA repair, this book focused on detailed experimental protocols and new techniques, plus a wonderful and concise introduction and explanation of each methods. In my opinion, this book refreshments my background knowledge, gives me an overview of recent progress in new methods and techniques, and ignites some new ideas to pursue further studies in this active field. Taken together, I think this is an essential handbook for professors and scientists in DNA damage and repair field and other related fields.

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