Adoptive Immunotherapy: Methods and Protocols

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Adoptive Immunotherapy: Methods and Protocols (Methods in Molecular Medicine)
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Publisher:  Humana Press
Number Of Pages:  520
Publication Date:  2004-11-30
Sales Rank:  3027515
ISBN / ASIN:  1588294064
EAN:  9781588294067
Binding:  Hardcover
Manufacturer:  Humana Press
Studio:  Humana Press
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Book Description:

An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy.