The Great King Who Swallowed Poison

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Mithradates（c．131—63 B．C．），the great king of Pontus and enemy of Rome，is said to have swallowed toxic substances systematically ，increasing the doses until he made himself immune from assassination by poison．
Ironically ，when he was defeated and cornered by the Romans，he tried to commit suicide by poison，only to find that it had no effect ．He had to get a soldier to kill him with a sword．